Antibodies to thyroid microsomal [2] and myeloperoxidase (MPO) are associated with graves’ disease and thyroiditis [3], antinuclear antibodies (ANA) and rheumatoid factor(RF) represent a serology hallmark in the diagnosis of systemic autoimmune rheumatic disease (SARD) such as systemic lupus erythematosus [4]. The gene discussed is MPO; the disease is systemic lupus erythematosus.