FGFR1 and cancer: Third, there were 3 DEGs in both “pathways in cancer” and “MAPK signaling pathway”, including fgfr1, pkc, and fgfr2. The transcriptomic results and qPCR data showed the fgfr1 and pkc are upregulated and downregulated by Ras1CA, respectively, while fgfr2 might be downregulated by Ras1CA (Figure 4C).