In the early post-transplant period, Evenepoel et al. demonstrated that elevated pre-transplant FGF-23 levels were the strongest predictor of post-transplant elevation of FGF-23, and FGF-23 independently predicted hypophosphatemia and inappropriately low 1,25-(OH)2D3 levels during the first 3 months post-transplant (56). Here, FGF23 is linked to hypophosphatemia.