CXCL8 and cystic fibrosis: The frequencies of the mutant alleles for CF patients and controls were: the MBL-O allele 0.231 and 0.233, the IL-8 -251T allele 0.576 and 0.569, AATS allele 0.012 and 0.014, and TNF2 allele 0.087 and 0.029, respectively.