Similarly, when the NK cells were assessed for susceptibility to undergo apoptosis, as seen in Figure 8 C & D, there was an increased susceptibility to undergo apoptosis from baseline values that peaked during acute infection (week 3 p.i.)in the control animals with a similar increase in the JAK3 inhibitor group except that the peak was noted at week 6 post infection in these animals. The gene discussed is JAK3; the disease is infection.