TNF and chorioamnionitis: In the three-factor analysis, the gene expression of key genes or proteins discussed in our manuscript (i.e. TNF-α, IL-1β, IL-6, cytokeratins, PLAC8, CXCL12, PECAM1, LAMB3, SCEL, DSG2) had the same up- or downregulation regardless of chorioamnionitis with the exception of MMP1. MMP1 gene expression was upregulated in GBS animals without chorioamnionitis, but similar to controls in the two animals with chorioamnionitis.