Investigators have reported a higher risk for RDS in neonates who carry the surfactant protein A1(SP-A1) 6A2 allele [11], surfactant protein B(SP-B) 131Thr allele [12], or surfactant protein C(SP-C) 138Asn allele [13]. This evidence concerns the gene SFTPA1 and newborn respiratory distress syndrome.