The gene is a part of a pathway in which other genes have been strongly associated with autism (development of the CNS, neurogenesis, neuronal migration, neuron projection, synaptogenesis, synaptic transmission) or is a part of a biochemical pathway from in which other genes have been strongly associated with autism (e.g., TSC/mTOR, MET receptor tyrosine kinase pathways). This evidence concerns the gene NTRK1 and autism.