CFTR and pancreatic neoplasm: Whereas there is no disagreement concerning the adequacy of a non-smoking advice other reports find a modest increased risk for carriers of disease-relevant CFTR mutations (OR:1.4; 95%CI: 1.04–1.89) and are more reluctant concerning the role of CFTR mutations as risk factors of pancreatic cancer (Whitcomb, 2004; McWilliams et al., 2010).