In addition, 1α,25(OH)2D3 inhibits glucuronidation and so, inactivation of androgen in prostate cancer cells through the repression of UDP-glucuronosyltransferases (UGT) 2B15 and 2B17, which is counterintuitive given the growth promoting action of androgen and the antiproliferative effect of 1α,25(OH)2D3 in prostate cancer cells (Kaeding et al., 2008). The gene discussed is B3GAT2; the disease is Familial prostate cancer.