OGG1 and noise induced hearing loss: Many epidemiological and functional studies have suggested that the Ser326Cys polymorphism (rs1052133) in exon 7 of hOGG1 gene may affect the activity of hOGG1 enzyme [25], [26] and may therefore serve as a genetic marker for susceptibility to many diseases [27], [28], [29], [30]; however, thus far, there have been no studies of association between the hOGG1 Ser326Cys polymorphism and risk of NIHL.