Because the initiation of the immune response requires efficient engagement of antigen with immature dendritic cells, we fused DNA encoding portions of the circumsporozoite protein (CSP) from either the mouse malaria strain Plasmodium yoelii or the human malaria strain Plasmodium falciparum to DNA encoding the chemokine macrophage inflammatory protein-3α(MIP3α), also known as CCL20. The gene discussed is CCL20; the disease is malaria.