IL18 and hypertensive disorder: Subsequently, using univariate Cox regression analysis, we found several potential factors associated with the risk of all-cause mortality, including old age, prevalent CAD, hypertension, low serum albumin level, and increased serum IL-18 concentrations, and less negative GLS (all p<0.05 except for the reduced GLS [p = 0.05, marginal significance], Table 4).