The breast cancer susceptibility variant rs3817198 in LSP1 [OR per allele C = 1.12 (1.03–1.22), p = 0.011], the lung cancer SNP rs3131379 in the MHC region in chromosome 6 (6p21.33) [OR per allele T = 1.16 (1.01–1.33), p = 0.030] and the prostate cancer variant rs10993994 in MSMB [OR per allele T = 1.09 (1.01–1.18), p = 0.036] were each associated with an increased risk of overall NHL. The gene discussed is MSMB; the disease is lung cancer.