Comprehensive studies using rNanog1 from NTERA-2 and rNanogP8 proteins from multiple somatic cancer cells further suggest that Nanog1 and NanogP8, which are >99% identical at the aa levels, seem to possess unique INTRINSIC biochemical properties that can allow them to adopt multiple protein conformations and consequently migrate at multiple apparent M.W. The rNanogP8 proteins made from 4 PCa (LNCaP, and HPCa1, 5, and 6) cell types all migrate at 42 kD as the major band on both WB (Fig. 6) and IP (Fig. 7A–B) analyses. The gene discussed is NANOGP8; the disease is cancer.