At 48 hours post LPS exposition to the lung, an over-expression of both CD86 and CD206 (30.7±2.7% and 29.3±3.1% respectively in COPD/Control group compared to 18.8±3.2% and 22.1±2.3% in Control/Control group) was observed (Figure 6a) while no statistical variation was detected for CD197 and CD150 (Figure 6b). The gene discussed is CCR7; the disease is chronic obstructive pulmonary disease.