In monocytes of 25 SLE patients and 15 HCs, we assessed the expression levels of 11 IFIGs previously assessed in monocytes from patients with primary Sjögren syndrome (pSS) (IFI27, IFI44L, IFIT3, IFITM1, SERPING1, IFIT1, IFIT2, LY6E, IFI44, XAF1, and MXA) [24], and the expression of which was also found to be increased in SLE patients [2,3,33,34]. The gene discussed is LY6E; the disease is systemic lupus erythematosus.