Overall, the analyses included the 4 most relevant groups of mice that could provide insights into the tumor-promoting roles of factors resulting out of the activation of Ras by TNFα (Figure 6A): (1) CellsControlCMControl; (2) CellsControlCMRas-G12V+TNFα; (3) CellsRas-G12V+TNFαCMControl; (4) CellsRas-G12V+TNFαCMRas-G12V+TNFα. The gene discussed is TNF; the disease is neoplasm.