Supporting a mechanism in which WT-Ras has been turned into an active entity, and in line with the fact that the MEK-Erk pathway mediates many of the Ras-induced activities [1], MEK-dependent pathways were involved in the ability of TNFα to induce CXCL8 expression in WT-Ras-expressing tumor cells. Here, MAP2K7 is linked to neoplasm.