We retrospectively analyzed all prognostic factors, including patient characteristics (sex, age, ECOG performance status), tumor characteristics (tumor site in rectum, tumor size, KIT, CD34, MI/50 HPF, NIH categories, Miettinen categories, necrosis, histological subtype, and mutational status), surgical management (type of procedure, radical vs conservative surgery, margins [R0 vs R1 vs R2 or R0 vs R1-R2 or R0-R1 vs R2], tumor rupture, surgery-related complications), and medical treatment (imatinib treatment group vs non-imatinib treatment group). This evidence concerns the gene CD34 and neoplasm.