Effects of FKBP5 polymorphisms on dexamethasone-induced suppression of cortisol have been reported in interaction with child abuse-related PTSD, inasmuch as risk variants in various FKBP5 polymorphisms interacted with PTSD status in predicting hyper-suppression of cortisol (75, 89). Here, FKBP5 is linked to post-traumatic stress disorder.