FTMT and Alzheimer disease: It was also found that, in the pathological conditions associated with mitochondrial iron overload, such as Alzheimer’s disease, PD, and sideroblastic anemia, the FtMt expression was largely induced (Cazzola et al., 2003; Shi et al., 2010; Wang et al., 2011; Wu et al., 2013; Yang et al., 2013).