However, existent evidence indicated that PSCs derived Galectin-1 might play an important role on the progression of PDAC, and there is a good prospect that it is associated with several aspects as follows: First, Galectin-1 supports metastasis formation, because it facilitates interactions between tumor cells and endothelium cells[49], [50], mediates cell-cell or cell extracellular matrix adhesion[51], promotes cancer cell migration, growth, and metastasis[52]. This evidence concerns the gene LGALS1 and cancer.