VIM and glaucoma: In the serum and aqueous humor of glaucoma patients general complex autoantibody patterns against retinal and optic nerve antigens were found [16], [17] but also more specific autoantibody changes such as an up- regulation of abs against e.g. alpha foldrin [16], [17] and Hsp 70 [18], and a down-regulation of abs against αB Crystallin and Vimentin [18] leading to the conclusion that there is a role for the autoantibodies in the pathogenesis of glaucoma.