On one hand, angiotensin II, by binding to angiotensin II type 1 receptor [5], leads to vascular constriction, endothelial cell migration, proliferation and hypertrophy and increases uptake and oxidation of LDL by endothelial cells as well as oxyradical production, thus leading to endothelial dysfunction [31]. This evidence concerns the gene AGTR1 and endothelial dysfunction.