To further characterize chemokine – receptor expression and identify an appropriate model for studying the function of CXCL12 in PDAC,primary patient-derived and established pancreatic cancer cell lines were analyzed through RT-PCR using our previously optimized primer sets for CXCL12, CXCR4, and CXCR7 [24], [43]. Here, ACKR3 is linked to familial pancreatic carcinoma.