TLR4 and hydrops fetalis: BF from Cav-3 KO brains showed increased expression of PSD-95, NR2B, NR1A, and TrkB (Figure 3A) compared to Cav-1 KO, yet the pattern-recognition receptor TLR4 was nearly lost in HF from Cav-3 KO brains and decreased in Cav-1 KO (Figure 3B).