Considering the well-established capacity of resistance training for increasing both muscle mass and strength, as well as improving the lipid profile, adiposity and obesity-associated inflammation, we have sought to investigate the effects of a resistance training program, mainly composed of concentric contractile force production on plasma FABP4, apoA-I and lipids profile in plasma and liver tissue in Streptozotocin-induced diabetic rats. Here, FABP4 is linked to obesity due to melanocortin 4 receptor deficiency.