There was significant, moderate correlation of myocardial involvement detected by T1 and ECV to indices of SSc disease activity and severity: ECV and mRSS (R 0.60, p = 0.03), ECV and SSc VDAI (RS 0.60, p = 0.04); native T1 and mRSS (R 0.55, p = 0.02), native T1 and SSc VDAI (RS 0.55, p = 0.05), native T1 and serum CRP (RS 0.41, p = 0.01) as shown in Figure 3. This evidence concerns the gene CRP and systemic sclerosis.