The ratio of Th1/Th2 in HIV + and HIV- TB patients showed no difference before treatment whereas the ratio of IFN-γ/IL-4 and IFN-γ/IL-10 showed a significant difference before and after treatment in HIV negative TB cases where as none of the Th1/Th2 cytokines ratio showed a significant difference after treatment in HIV positive TB cases. Here, IL4 is linked to tuberculosis.