Longitudinal assessment of the plasma cytokine profile showed that out of the 17 cytokines measured, the plasma level of IFN-γ, IL-4, IP-10, MCP-3 and MIP-1β significantly changed after completion of anti-TB treatment in HIV negative TB patients whereas in HIV positive TB patients none of the cytokines and chemokines showed significant difference after anti TB treatment. Here, IL4 is linked to tuberculosis.