Longitudinal assessment of the plasma cytokine profile showed that out of the 17 cytokines measured, the plasma level of IFN-γ, IL-4, IP-10, MCP-3 and MIP-1β significantly changed after completion of anti-TB treatment in HIV negative TB patients whereas in HIV positive TB patients none of the cytokines and chemokines showed significant difference after anti TB treatment. The gene discussed is CCL7; the disease is tuberculosis.