USPSTF and HIVMA guidelines include annual breast and colorectal cancer screeing for women age 50 and older and cervical cancer screening starting at age 21, conducted annually if two normal Pap tests are documented during the first year after HIV diagnosis [6] and the CD4 count is >200 cells/μL and increasing to every 6 months if the CD4 count is <200 cells/μL [8]. This evidence concerns the gene CD4 and colorectal cancer.