On the other hand, two nontoxic enzymes with high PLA2 activity isolated from Cerastes cerastes snake venomcalled CC-PLA2-I and CC-PLA2-II inhibited the migration and adhesion of IGR39 melanoma and HT1080 fibrosarcoma cells to fibrinogen and fibronectin [44]. This evidence concerns the gene PLA2G6 and melanoma.