BRCA1 and non-small cell lung carcinoma: Some studies demonstrated that NSCLC patients with high BRCA1 mRNA expression had low efficacy with cisplatin therapy but high efficacy with the antimicrotubule drugs docetaxel and vinorelbine, which suggested that BRCA1 may be an important prognostic indicator and predictive factor for chemotherapy success in NSCLC patients [6, 7].