TBX1 and chordoma: Finally, since a positive stain for brachyury was also demonstrated in extra-axial chordomas [12, 30, 31], immunohistochemistry against this protein may be used in order to distinguish chordomas arisen in the soft tissues towards histological mimickers such as myoepithelioma [12, 30, 31], which is of striking importance due to the tendency to grow and recur of the former.