As the main hypothesis behind the deregulation of the female module 2.1 and the male module is a reactivation of the Epstein - Barr Virus infection in B cells (see discussion), the expression of 5 viral genes (BZLF1, EBNA1, EBNA2, LMP1 and LMP2) has been measured by qPCR to test it. The gene discussed is PSMB9; the disease is Epstein-Barr virus infection.