Notably, it has been described that the Epstein-Barr virus infection promotes transcriptional activity through the induction of the expression of all subunits of TFIIIC and BDP1 (a TFIIIB subunit), which are necessary for POLIII-mediated transcription initiation [13] and also induces the expression of MIR21 [14]. This evidence concerns the gene MIR21 and Epstein-Barr virus infection.