IGHE and systemic lupus erythematosus: To further advance the understanding of IgE in SLE we measured the levels of IgE’s with specificity to the most common SLE antigens, dsDNA, Sm, SSA (Ro), and SSB (La) in a sample of 196 SLE subjects in France or the US with a mean age of 41.5±12.7 and 43.6±15.3 years and disease duration of 13.5±8.5 and 16.6±11.9 years, respectively (Table 1).