GGCX and pulmonary embolism: mir3179 and vast amount of other miRNA molecules such as mir338, mir3118, mir657, mir1268 and mir650 down regulates GGCX, and sometimes these down-regulators are regulated by other miRNA molecules such as mir650 which is master regulator controlling the GGCX downstream pathway, which also has been implicated in several disease processes such as pulmonary embolism, thrombosis of vein, abdominal hemorrhage and bleeding of tissue.