SPHK1 and uterine cancer: When the SK1 expression levels in normal tissues were assumed to be 1, the mRNA level increases ranged from 1.48-fold in uterine cancer to 7.86-fold in salivary gland carcinoma, and the protein level increases ranged from 1.45-fold in non-Hodgkin’s lymphoma to 8.88-fold in gastric cancer (Figure 3).