CD40 and infection: Figure 3A shows representative plots of flow cytometric analysis of CD86 and CD 40 on the surface of DCs following infection with PA103ΔUΔT and Yorkhill 1 strains of PA as well as exposure to heat killed Candida albicans. These examples all show a marked upregulation of these activation markers on the surface of DCs. This was quantified for both CD86 and CD40 for a range of strains as shown in Figure 3B and 3C respectively.