In our previous mutational screen in a Chinese sporadic CHD cohort, a low-coverage (100×) exome sequencing of 18 pooled samples identified a splice-site mutation (chr8:13072284, C>G, reference assembly: hg19) of the deleted in liver cancer 1 (DLC1) gene in a patient who has atrial septal defect (ASD). The gene discussed is DLC1; the disease is coronary artery disorder.