AMBRA1 and colorectal carcinoma: The function of Ambra1 in autophagy and apoptosis has been explored in vitro in embryonic stem cells and human fibroblast 2FTGH (2F) cells [13], but the role of Ambra1 in CRC cell lines has not been reported in the literature, and the role of this ATG protein in the autophagy and apoptosis pathways in CRC cell lines is unknown.