Upon C. jejuni infection gnotobiotic IL-10−/− mice get readily colonized by the pathogen and display acute enterocolitis within one week p.i.mimicking severe campylobacteriosis in humans, whereas gnotobiotic or with human microbiota reassociated wildtype mice display intestinal pro-inflammatory immune responses but no overt clinical symptoms such as bloody diarrhea upon C. jejuni infection [18]. This evidence concerns the gene IL10 and campylobacteriosis.