Src, the prototypical member of the large Src-family of non-receptor tyrosine kinases, is activated downstream of numerous receptors, and present in many cells and tissues in which ERG1 or EAG1 are important, including immune cells [16], cancer cells [12], [15], [17] and cardiac and vascular smooth muscle [18], [19]. This evidence concerns the gene KCNH2 and cancer.