SERPINE2 and chronic obstructive pulmonary disease: In our study SNPs rs729631 (OR = 2.558, 95% CI: 1.131–5.788, p = 0.024), rs975278 (OR = 2.558, 95% CI: 1.131–5.788, p = 0.024), rs7583463 (OR = 2.407, 95% CI: 1.212–4.781, p = 0.012) of SERPINE2 showed significant association with COPD under recessive model.