To determine if modulations of AGR-2 levels during tumor growth and metastasis is associated with altered integrin levels and function, we determined the expression of a panel of integrins (α4, α5, αV, β1, β3, β4, β5 integrins) in PC3AGR−2sh and PC3Control cells by Western blotting. The gene discussed is AGR2; the disease is neoplasm.