SDC1 and myocardial infarction: Specifically, the syndecan-1 gene is upregulated after vascular injury[22] and has been found to be critical for corneal and epithelial wound healing,[23] cardioprotection following myocardial infarction,[24] and in clearing triglyceride-rich lipoproteins.[25] Recent studies have shown that it has a role in regulating vascular smooth muscle cell proliferation in response to PDGF and in intimal formation following ligation injury.[26] Thus, syndecan-1 has the potential to regulate multiple aspects of vascular disease.