[4], [5], [6]. So far, a few reports have shown that Rab27a can promote proliferation and invasion and can repress apoptosis. However, these studies were only based on functional assays in a glioma cell line [7], [8]; the comprehensive expression patterns and effect of Rab27a on the occurrence and development of glioma are still unclear. The gene discussed is RAB27A; the disease is central nervous system cancer.