TLX1 and B-cell non-Hodgkin lymphoma: Transgenic mice in which the TLX1 gene is placed under the control of the immunoglobulin heavy chain (IgH) promoter and enhancer, thus directing its expression predominantly to the B cell compartment (IgHμ-TLX1Tg mice), develop mature marginal zone B-cell lymphomas after an extended latency [11].