TPO and hypothyroidism: In the screening of 4,800 pregnant women at eight-week gestation by the research team led by Prof. Teng WP, 6.15% of the subjects were determined to have sub-clinical hypothyroidism (9.5% for this project), 1.11% exhibited hypothyroxinemia (19.0% for this project), and 9.6% were TPO Ab positive (1.6% for this project).