SENP1 expression levels have been demonstrated to be elevated during prostate pathogenesis [26]–[27] while those of CYP24A1 are increased in cancers of the prostate, colon, ovary, and lung, a number of which are known to be insensitive to the growth-regulatory effects of vitamin D [28], [29]. The gene discussed is CYP24A1; the disease is prostatitis.