When algorithm II prediction was observed, the statistical association was similar, with a median CD4+T cell count of 361.0 (IQR: 245.0–557.5) cells/μl in the CXCR4-tropic infection compared to a median CD4+T cell count of 457.0 (IQR: 312.2–564.7) cells/μl in the CCR5-tropic infection (Z = 2.391, P = 0.017), (Fig. 4). Here, CD4 is linked to infection.